The Ministry of Food and Drug Safety (MFDS) has released Notice No. 2025-433, temporarily designating six new substances, including Fluetonitazen, as narcotics under the Narcotics Control Act due to their potential public health risks. The designation remains valid for three years from the announcement date and prohibits possession, ownership, or handling of these substances without MFDS approval. This notice consolidates previous temporary narcotic listings to strengthen compliance and public awareness.
The document also compares international classifications, noting that Australia lists similar substances under Schedule 9, while the UK and Germany apply their own classifications—reflecting global regulatory concern. These substances show high affinity for cannabinoid receptors (CB1), leading to psychoactive effects similar to THC and an increased potential for abuse. Reported side effects include neurotoxicity, sensory loss, dizziness, and hallucinations, reinforcing the need for stringent regulation, and continued research.
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