On June 1, 2026, the European Chemicals Agency (ECHA) opened a 60-day public consultation on a proposal submitted by Germany to revise the harmonised classification and labelling (CLH) of esbiothrin (CAS No. 260359-57-7) under the European Union’s Classification, Labelling and Packaging (CLP) Regulation. Stakeholders are invited to submit comments by July 31, 2026 on the proposed hazard classifications and supporting scientific data. The proposal seeks to update the existing Annex VI entry by assigning more stringent hazard classifications to esbiothrin, including Acute Toxicity Category 3 (oral), Reproductive Toxicity Category 2 (suspected of damaging the unborn child), Specific Target Organ Toxicity – Single Exposure Category 1, and Specific Target Organ Toxicity – Repeated Exposure Category 2. The dossier also proposes maintaining classifications for acute aquatic and chronic aquatic toxicity with increased M-factors of 100. Germany further recommends removing esbiothrin from the current grouped Annex VI entry covering allethrin-related substances and establishing a substance-specific classification. The consultation covers multiple hazard classes, including acute toxicity, skin and eye effects, sensitisation, mutagenicity, carcinogenicity, reproductive toxicity, specific target organ toxicity, aspiration hazard, environmental hazards, and ozone layer hazards. Comments received during the consultation will be evaluated as part of ECHA’s harmonised classification and labelling process before the Risk Assessment Committee (RAC) adopts its scientific opinion.
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